What can thick secretions from cystic fibrosis lead to?

Thick secretions in cystic fibrosis primarily result from the inability of the body to transport chloride and water across cell membranes effectively. This leads to the production of viscous mucus that can obstruct airways. When the airways are blocked, it creates an environment conducive to the growth of bacteria, increasing the risk of lung infections. As these infections become more severe and recurrent, they can lead to further lung damage and ultimately reduce respiratory function. The combination of airway obstruction due to thick secretions and the resultant chronic infections is a hallmark of cystic fibrosis and is significantly associated with morbidity and mortality in affected individuals.